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Table 2 PADI4 haplotype frequencies in Caucasian individuals

From: Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case–control study

  PADI4 haplotype (frequencies) PADI4 haplotype (carriers)
  Haplotype 1 Haplotype 1B Haplotype 2/3 Haplotype 4 Haplotype 1 Haplotype 1B Haplotype 2/3 Haplotype 4
Controls 119 (58.3%) 6 (2.9%) 63 (30.9%) 16 (7.8%) 84 (82.4%) 6 (5.9%) 51 (50%) 14 (13.7%)
Patients 102 (50%) 1 (0.5%) 71 (34.8%) 30 (14.7%) 77 (75.5%) 1 (1%) 54 (52.9%) 28 (27.5%)
Odds ratio 0.71 0.16 1.2 2.0 0.66 0.16 1.1 2.4
95% confidence interval 0.48–1.1 0.02–1.4 0.79–1.8 1.1–3.8 0.33–1.3 0.02–1.3 0.65–1.9 1.2–4.8
P 0.11 0.12 0.46 0.04 0.30 0.12 0.78 0.02
  1. PADI4 haplotype and carrier frequencies in patients with rheumatoid arthritis (n = 102) and in healthy controls (n = 102) are presented. Results of univariate analyses (odds ratio, 95% confidence interval) and Fisher's exact tests are indicated.