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Table 2 PADI4 haplotype frequencies in Caucasian individuals

From: Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case–control study

 

PADI4 haplotype (frequencies)

PADI4 haplotype (carriers)

 

Haplotype 1

Haplotype 1B

Haplotype 2/3

Haplotype 4

Haplotype 1

Haplotype 1B

Haplotype 2/3

Haplotype 4

Controls

119 (58.3%)

6 (2.9%)

63 (30.9%)

16 (7.8%)

84 (82.4%)

6 (5.9%)

51 (50%)

14 (13.7%)

Patients

102 (50%)

1 (0.5%)

71 (34.8%)

30 (14.7%)

77 (75.5%)

1 (1%)

54 (52.9%)

28 (27.5%)

Odds ratio

0.71

0.16

1.2

2.0

0.66

0.16

1.1

2.4

95% confidence interval

0.48–1.1

0.02–1.4

0.79–1.8

1.1–3.8

0.33–1.3

0.02–1.3

0.65–1.9

1.2–4.8

P

0.11

0.12

0.46

0.04

0.30

0.12

0.78

0.02

  1. PADI4 haplotype and carrier frequencies in patients with rheumatoid arthritis (n = 102) and in healthy controls (n = 102) are presented. Results of univariate analyses (odds ratio, 95% confidence interval) and Fisher's exact tests are indicated.