|
PADI4 haplotype (frequencies)
|
PADI4 haplotype (carriers)
|
---|
|
Haplotype 1
|
Haplotype 1B
|
Haplotype 2/3
|
Haplotype 4
|
Haplotype 1
|
Haplotype 1B
|
Haplotype 2/3
|
Haplotype 4
|
---|
Controls
|
119 (58.3%)
|
6 (2.9%)
|
63 (30.9%)
|
16 (7.8%)
|
84 (82.4%)
|
6 (5.9%)
|
51 (50%)
|
14 (13.7%)
|
Patients
|
102 (50%)
|
1 (0.5%)
|
71 (34.8%)
|
30 (14.7%)
|
77 (75.5%)
|
1 (1%)
|
54 (52.9%)
|
28 (27.5%)
|
Odds ratio
|
0.71
|
0.16
|
1.2
|
2.0
|
0.66
|
0.16
|
1.1
|
2.4
|
95% confidence interval
|
0.48–1.1
|
0.02–1.4
|
0.79–1.8
|
1.1–3.8
|
0.33–1.3
|
0.02–1.3
|
0.65–1.9
|
1.2–4.8
|
P
|
0.11
|
0.12
|
0.46
|
0.04
|
0.30
|
0.12
|
0.78
|
0.02
|
- PADI4 haplotype and carrier frequencies in patients with rheumatoid arthritis (n = 102) and in healthy controls (n = 102) are presented. Results of univariate analyses (odds ratio, 95% confidence interval) and Fisher's exact tests are indicated.