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Table 2 Anti-CCP and IgM RF as predictors of radiographic joint destruction after 5 years

From: Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis

  Odds ratios (95% confidence intervals)
  Erosions Joint space narrowing Total
Anti-CCP2 (baseline) 1.91 (0.73–4.96) 1.64 (0.73–3.68) 1.90 (0.85–4.27)
Anti-CCP2 (first 3 years) 5.28 (1.45–19.2)a 2.8 (1.15–6.78)b 3.17 (1.30–7.69)c
IgM RF (baseline) 0.45 (0.17–1.17) 0.57 (0.23–1.39) 0.67 (0.28–1.65)
IgM RF (first 3 years) 0.70 (0.21–2.25) 1.03 (0.35–3.0) 0.88 (0.30–2.58)
  1. aP = 0.007; bP = 0.03; cP = 0.01. IgM RF, immunoglobulin M rheumatoid factor.