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Table 3 TNFα levels in high and low TNFα producing patient users and nonusers of antimalarial treatment

From: Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs

TNFα genotype Healthy controls Patients without antimalarial drugs Patients with antimalarial drugs p
  n TNFα (pg/ml)a n TNFα (pg/ml)a n TNFα (pg/ml)a  
High (AA/AG) 53 20.06 (125.63) 24 83.55 (171.64) 48 16.88 (54.89) 0.001
Low (GG) 162 18.83 (40.67) 45 58.56 (168.94) 54 26.00 (154.67) 0.516
  1. aValues are median (interquartile range). Differences between users and nonusers of antimalarial therapy were evaluated by the Mann-Whitney U test. TNF, tumor necrosis factor.