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Table 4 TNFα levels in high and low IL-10 producing patient users and nonusers of antimalarial treatment

From: Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs

IL-10 genotype Healthy controls Patients without antimalarial drugs Patients with antimalarial drugs p
  n TNFα (pg/ml)a n TNFα (pg/ml)a n TNFα (pg/ml)a  
Low (AA/AG) 179 18.55 (49.27) 56 80.88 (201.48) 79 20.94 (84.97) 0.005
High (GG) 36 21.74 (58.42) 12 51.91 (51.75) 23 20.03 (134.44) 0.797
  1. aValues are median (interquartile range). Differences between users and nonusers of antimalarial therapy were evaluated by the Mann-Whitney U test. TNF, tumor necrosis factor.