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Table 5 IL-10 and TNFα genotypes of systemic lupus erythematosus patients stratified by treatment

From: Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs

Treatment TNFα genotype IL-10 genotype
  High (AA/AG) Low (GG) High (GG) Low (AA/AG)
None/NSAIDS 6 (26.1) 17 (73.9) 4 (17.4) 19 (82.6)
Antimalarials 23 (57.5) 17 (42.5) 6 (15.0) 34 (85.0)
Corticosteroids 8 (28.6) 20 (71.4) 6 (22.2) 21 (77.8)
Antimalarials and corticosteroids 25 (41.7) 35 (58.3) 16 (26.7) 44 (73.3)
Immunosuppressive drugsa alone or with corticosteroids 13 (48.1) 14 (51.9) 3 (11.1) 24 (88.9)
Antimalarials, corticosteroids and immunosuppressive drugsa 5 (35.7) 9 (64.3) 3 (21.4) 11 (78.6)
  1. Values are n (%). aMethotrexate, azathioprine, cyclophosphamide, cyclosporine A or mycophenolate mophetil. NSAIDS, nonsteroidal anti-inflammatory drugs; TNF, tumor necrosis factor.