Table 5 IL-10 and TNFα genotypes of systemic lupus erythematosus patients stratified by treatment
From: Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs
Treatment | TNFα genotype | IL-10 genotype | ||
|---|---|---|---|---|
High (AA/AG) | Low (GG) | High (GG) | Low (AA/AG) | |
None/NSAIDS | 6 (26.1) | 17 (73.9) | 4 (17.4) | 19 (82.6) |
Antimalarials | 23 (57.5) | 17 (42.5) | 6 (15.0) | 34 (85.0) |
Corticosteroids | 8 (28.6) | 20 (71.4) | 6 (22.2) | 21 (77.8) |
Antimalarials and corticosteroids | 25 (41.7) | 35 (58.3) | 16 (26.7) | 44 (73.3) |
Immunosuppressive drugsa alone or with corticosteroids | 13 (48.1) | 14 (51.9) | 3 (11.1) | 24 (88.9) |
Antimalarials, corticosteroids and immunosuppressive drugsa | 5 (35.7) | 9 (64.3) | 3 (21.4) | 11 (78.6) |