Figure 2
From: Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis
Regional immunolocalisation of proteoglycan 4 (PRG4) with polyclonal antibody 06A10 in ovine tibial plateau cartilage. Lateral and medial tibial plateaux (LTP and MTP, respectively) from regions covered (COV) or uncovered (UNCOV) by the meniscus in sham-operated and meniscectomised (MEN) joints are shown, including enlarged views of respective surface zones as insets. Representative PRG4-positive (arrows) and PRG4-negative (asterisks) chondrocytes are indicated. Scale bar, 150 μm.