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Table 1 Characteristics of patients and treatments

From: Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure

Parameter Methotrexate All other DMARDs
Number 86 77
Age (years [mean ± SD]) 60.7 ± 12.9 63.6 ± 11.9
Rheumatoid Factor (% positive) 70.9% 64.9%
Sex (% female) 86.0% 79.2%
Disease duration (years [mean ± SD]; oMTX/rMTX) 9.5 ± 8.3/13.3 ± 8.6 7.5 ± 8.5/12.6 ± 8.6
Prior DMARDs (median [range]; oMTX/rMTX) 1 (0–6)/4 (2–9) 1 (0–8)/3 (2–10)
Baseline dose (mg/week [median (1st-3rd quartile)]; oMTX/rMTX) 10.0 (7.5–15.0)/15.0 (10.0–20.0) -/-
Base line CRP (mg/l [mean ± SD]; oMTX/rMTX) 33.4 ± 26.2/29.1 ± 31.0 15.2 ± 16.8/18.3 ± 23.0
Base line ESR (mm/hour [mean ± SD]; oMTX/rMTX) 47.0 ± 30.0/35.0 ± 22.0 30 ± 13/32 ± 22
  1. CRP, C-reactive protein; DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; oMTX, original methotrexate course; rMTX, re-employed methotrexate course; SD, standard deviation.