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Table 3 EASE results for differentially expressed genes identified in hybridization series 1 and 2

From: Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology

GO ID GO term Orthopedic biopsies Arthroscopic biopsies
   Rank Number of hits EASE score Rank Number of hits EASE score
GO:0007154 Cell communication 1 685 4.63 × 10-14 5 273 4.72 × 10-6
GO:0007155 Cell adhesion 2 166 3.29 × 10-10 7 72 8.51 × 10-6
GO:0009607 Response to biotic stimulus 4 199 5.89 × 10-9 3 90 1.30 × 10-6
GO:0006952 Defense response 5 181 1.60 × 10-8 2 84 7.69 × 10-7
GO:0009605 Response to external stimulus 6 273 3.00 × 10-8 1 126 1.56 × 10-7
GO:0006955 Immune response 7 166 1.12 × 10-7 4 78 1.63 × 10-6
GO:0007166 Cell surface receptor linked signal transduction 9 209 1.24 × 10-6 9 95 1.77 × 10-5
GO:0007160 Cell-matrix adhesion 10 31 2.98 × 10-5 121 9 2.32 × 10-1
GO:0009613 Response to pest/pathogen/parasite 11 107 3.66 × 10-5 6 55 6.78 × 10-6
GO:0009611 Response to wounding 21 61 1.43 × 10-3 8 36 1.44 × 10-5
GO:0006954 Inflammatory response 53 40 1.89 × 10-2 10 27 3.77 × 10-5
GO:0007165 Signal transduction 3 533 4.69 × 10-10 20 204 1.77 × 10-3
GO:0009987 Cellular process 8 1,303 1.95 × 10-7 15 519 4.28 × 10-4
  1. The table lists the top 10 gene ontology (GO) categories for the 4,175 genes that were differentially expressed between orthopedic biopsies and for the 1,536 differentially expressed genes that were found to vary between arthroscopic biopsies. Seven of the top 10 GO categories were common between the two biopsy types. In the columns headed 'Rank', category 1 is the most significant category and the category with the highest number is the least significant. EASE, Expression Analysis Systematic Explorer.