Figure 3From: Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeuticsReactions catalyzed by xanthine oxidase (also known as xanthine oxidoreductase). The enzyme exists in dehydrogenase and oxidase forms, accepting NAD+ in the former conformation and O2 in the latter. Reversible interconversion of the forms involves disulfide bond formation and disruption.Back to article page