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Table 3 Relationship between VDR genotype and clinical manifestation or laboratory profiles of SLE

From: Vitamin D receptor gene BsmIpolymorphisms in Thai patients with systemic lupus erythematosus

  BB % (ratio) n = 2 Bb % (ratio) n = 22 bb % (ratio) n = 77 Total % (ratio)
Malar rash 50 (1/2) 54.54 (12/22) 54.54 (42/77) 54.45 (55/101)
Discoid rash 0 (0/2) 27.27 (6/22) 31.16 (24/77) 29.70 (30/101)
Photosensitivity 50 (1/2) 31.81 (7/22) 38.96 (30/77) 37.62 (38/101)
Oral ulcer 50 (1/2) 31.81 (7/22) 36.36 (28/77) 35.64 (36/101)
Arthritis 100 (2/2) 77.27 (17/22) 70.12 (54/77) 72.27 (73/101)
Serositis 50 (1/2) 18.18 (4/22) 9.09 (7/77) 11.88 (12/101)
- Pericardial effusion 0 (0/2) 13.63 (3/22) 7.79 (6/77) 8.91 (9/101)
- Pleural effusion 50 (1/2) 9.09 (2/22) 6.49 (5/77) 7.92 (8/101)
Renal disorder 50 (1/2) 68.18 (15/22) 64.93 (50/77) 65.34 (66/101)
Neurologic disorder 0 (0/2) 9.09 (2/22) 20.77(16/77) 17.82 (18/101)
- Seizure 0 (0/2) 9.09 (2/22) 15.58 (12/77) 13.86 (14/101)
- Psychosis 0 (0/2) 0 (0/22) 9.09 (7/77) 6.93 (7/101)
Hematologic disorder     
- Leukopenia 50 (1/2) 40.90 (9/22) 44.15 (34/77) 43.56 (44/101)
- Thrombocytopenia 0 (0/2) 9.09 (2/22) 18.18 (14/77) 15.84 (16/101)
Immunologic disorder     
- Anti-DNA 0 (0/2) 71.42 (15/21) 56.66 (34/60) 60.49 (49/81)
- Anti-Sm 0 (0/2) 57.14 (8/14) 32.60 (15/46) 37.09 (23/62)
ANA 100 (2/2) 100 (22/22) 98.68 (75/76) 99 (99/100)
- Homogenous pattern 50 (1/2) 50 (11/22) 48.68 (37/76) 49 (49/100)
- Rim pattern 0 (0/2) 40.90 (9/22) 44.73 (34/76) 33 (33/100)
- Nucleolar pattern 0 (0/2) 0 (0/22) 3.94 (3/76) 3 (3/100)
- Speckle pattern 50 (1/2) 45.45 (10/22) 59.21 (45/76) 56 (56/100)
  1. ANA = anti-nuclear antibodies; bb = excisable allele homozygote; Bb = heterozygote; BB = non-excisable allele homozygote; SLE, systemic lupus erythematosus; Sm = Smith; VDR, vitamin D receptor.