Figure 1From: Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupusDCs accumulate with age in mice with lupus. (a) To study DCs, we analyzed the total population of splenocytes in mice 6 to 8 weeks old (young) and in mice 6 to 9 months old (old) and gated for CD11c+ cells that were negative for the B cell marker CD19. (b,c) Percentages (b) and absolute numbers (c) of DCs gated as in (a). Each circle represents the percentage or absolute number of CD11c+ cells in one individual mouse, and the horizontal bars represent the average of each group. Results of the Mann-Whitney test analyses are shown. N.S. indicates p > 0.05.Back to article page