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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis

Figure 5

Ultrastructural in situ hybridization for cartilage oligomeric protein (COMP) mRNA in samples taken from the area with macroscopically normal appearance of osteoarthritic tissue. (a) A type 2 cell is depicted with staining for COMP mRNA (arrows); inset shows a higher magnification. (b) Staining for COMP mRNA (arrow) in a type 1 cell. (c) Note that the gold particles (arrow) are found only in the cytoplasm adjacent to the rough endoplasmic reticulum. Bars, 0.3 μm in (a) and (b) and 0.25 μm in (c) and inset (a). n, nucleus.

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Arthritis Research & Therapy

ISSN: 1478-6362

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