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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis

Figure 1

Expression of TNF-α, IL-1β, stromelysin and collagenase I in synovial tissues. Results are presented as percentage of GAPDH expression on a logarithmic scale with maximum, minimum, quartiles and median. Where indicated with an asterisk, there were significant differences from normal tissues (p < 0.05; Mann–Whitney). Rheumatoid arthritis (RA) versus normal donors (ND): IL-1β, p = 0.0097; TNF-α, p = 0.008; stromelysin, p = 0.0009; collagenase I, p = 0.0002. Osteoarthritis (OA) versus ND: IL-1β, p = 0.1451; TNF-α, p = 0.0013; stromelysin, p = 0.038; collagenase I, p = 0.0012. RA versus OA: IL-1β, p = 0.0397; TNF-α, p = 0.9591; stromelysin, p = 0.0124; collagenase I, p = 0.0266. GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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Arthritis Research & Therapy

ISSN: 1478-6362

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