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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis

Figure 3

Expression of BMP-4 and BMP-5 in synovial tissues detected by semiquantitative PCR. Results are presented as percentage of GAPDH expression on a logarithmic scale with maximum, minimum, quartiles and median. Where indicated, there were significant differences from normal tissues (asterisk) or osteoarthritis (OA) (hash sign) (p < 0.05, Mann–Whitney). Rheumatoid arthritis (RA) versus normal donors (ND): bone morphogenetic protein (BMP)-4, p = 0.0005; BMP-5, p = 0.0016. OA versus ND: BMP-4, p = 0.0143; BMP-5, p = 0.0011. RA versus OA: BMP-4, p = 0.0180; BMP-5, p = 0.9215. GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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Arthritis Research & Therapy

ISSN: 1478-6362

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