Table 1 Interventions that potentially reduce progression of structuralchanges in osteoarthritis
Nonpharmacological and preventative strategies | Pharmaceutical therapies |
|---|---|
Weight loss | Inhibition of MMPs, IL-1β |
Physical activity | Bone antiresorptive agents |
Partial meniscectomy | Neutraceuticals: glucosamine sulphate, chondroitin sulphate |
Valgus osteotomy(?) | Intra-articular interventions: steroids, viscosupplementation |