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Figure 3 | Arthritis Research & Therapy

Figure 3

From: The in vivoexpression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus

Figure 3

Autoantibody profiles of the experimental cohorts at 12 months of age. (a) IgG anti-ssDNA titres in the serum of Apcs-/-, wt.DNase I. Apcs-/- and ash.DNase I. Apcs-/- mice. Values are expressed in arbitrary ELISA units (AEU) related to a standard positive sample that was assigned a value of 100 AEU. Each symbol represents one mouse. (b) Anti-histone titres in the same groups of mice as in (a), and statistics were performed as described in the Materials and methods with significant differences if p < 0.05. Error bars indicate standard error of the mean. NS, not significant.

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