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Table 1 Analysis of cell populations by flow cytometry

From: The in vivoexpression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus

  C57BL/6 (n = 3) ash.DNase I (n = 5) P
Spleen    
   CD4+ of all lymphocytes (%) 18.1 ± 1.4 18.0 ± 1.6 NS
   B/T ratio 6.3 ± 0.2 5.7 ± 1.0 NS
   CD4/CD8 ratio 1.6 ± 0.1 1.5 ± 0.2 NS
   CD4+ expressing CD62L+ (%) 73.2 ± 2.6 72.8 ± 3.1 NS
Thymus    
   CD4/CD8+ lymphocytes (%) 81.6 ± 1.5 79.8 ± 2.4 NS
   CD4+ CD8- lymphocytes (%) 3.6 ± 0.3 3.9 ± 0.4 NS
  1. ash.DNase I = actin-resistant, salt-resistant and hyperactive mutant of DNase I; NS, not significant.