Skip to main content

Table 1 Analysis of cell populations by flow cytometry

From: The in vivoexpression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus

 

C57BL/6 (n = 3)

ash.DNase I (n = 5)

P

Spleen

   

   CD4+ of all lymphocytes (%)

18.1 ± 1.4

18.0 ± 1.6

NS

   B/T ratio

6.3 ± 0.2

5.7 ± 1.0

NS

   CD4/CD8 ratio

1.6 ± 0.1

1.5 ± 0.2

NS

   CD4+ expressing CD62L+ (%)

73.2 ± 2.6

72.8 ± 3.1

NS

Thymus

   

   CD4/CD8+ lymphocytes (%)

81.6 ± 1.5

79.8 ± 2.4

NS

   CD4+ CD8- lymphocytes (%)

3.6 ± 0.3

3.9 ± 0.4

NS

  1. ash.DNase I = actin-resistant, salt-resistant and hyperactive mutant of DNase I; NS, not significant.