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Figure 3 | Arthritis Research & Therapy

Figure 3

From: The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis

Figure 3

Secretion of S100A8 and S100A9 proteins from isolated synovial tissue (ST) cells of rheumatoid arthritis (RA) and osteoarthritis (OA). Freshly isolated ST cells (1 × 106 cells per ml in culture medium with 10% fetal calf serum) were incubated without any stimulation for 72 hours. Culture supernatants were measured in duplicate for the S100A8/A9 heterodimer by enzyme-linked immunosorbent assay. Values are the mean ± standard error of the mean. n, number of samples tested.

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