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Table 1 Genotype and allele frequencies of PTPN22 1858 T/C SNP in controls and patients with RA

From: Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

 

Genotype frequency

Allele frequency

 

CT

CT and TT

TT

T

Controls (n = 349)

18.3 (64)

19.2 (67)

0.9 (3)

10.0 (70)

RA (n = 390)

33.3 (130)

37.9 (148)

4.6 (18)

21.3 (166)

OR (95% CI)

2.23a (1.59–3.13)

2.57a (1.85–3.58)

5.58b (1.85–16.79)

2.43a (1.81–3.26)

  1. Values are the frequency in percent with absolute number of genotypes or alleles given in parentheses. Odds ratios (OR), 95% confidence intervals (CI) and p values are for the comparison of frequencies of the indicated markers in the patients compared to the controls. Level of significance: ap < 0.001 and bp < 0.005, power for all calculations α > 0.8.
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Arthritis Research & Therapy

ISSN: 1478-6362

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