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Table 1 Genotype and allele frequencies of PTPN22 1858 T/C SNP in controls and patients with RA

From: Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

  Genotype frequency Allele frequency
  CT CT and TT TT T
Controls (n = 349) 18.3 (64) 19.2 (67) 0.9 (3) 10.0 (70)
RA (n = 390) 33.3 (130) 37.9 (148) 4.6 (18) 21.3 (166)
OR (95% CI) 2.23a (1.59–3.13) 2.57a (1.85–3.58) 5.58b (1.85–16.79) 2.43a (1.81–3.26)
  1. Values are the frequency in percent with absolute number of genotypes or alleles given in parentheses. Odds ratios (OR), 95% confidence intervals (CI) and p values are for the comparison of frequencies of the indicated markers in the patients compared to the controls. Level of significance: ap < 0.001 and bp < 0.005, power for all calculations α > 0.8.