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Table 4 Radiographic progression in RA patients according to the presence or absence of the PTPN22 1858T allele

From: Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients

 

CC (n = 78)

CT/TT (n = 45)

P value

Larsen score at study entry

0 (0–2.5)

0 (0–4.7)

0.612

Larsen score after 1 year

2.0 (0–12.2)

11.5 (0–20.0)

0.061

Larsen score after 2 years

10.0 (0–26.0)

18.5 (2.0–34.5)

0.076

Larsen score after 4 years

16.0 (2.0–30.0)

24.0 (4.7–41.5)

0.136

Larsen score after 6 years

22.0 (10.7–39.2)

37.0 (15.25–52.7)

0.159

  1. Data are medians and interquartile range (IQR) for the comparison between PTPN22 risk allele negative and positive prospectively followed patients (n = 123). Levels of significance are given as determined by univariate analysis, power for all comparisons α < 0.8.
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Arthritis Research & Therapy

ISSN: 1478-6362

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