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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ – prostaglandin E2dependent proliferation of growth plate chondrocytes

Figure 4

Proliferation assay with selective and unselective cyclooxygenase (COX) inhibitors. The effect of selective and unselective COX inhibitors on chondrocyte proliferation was assessed by [3H]-thymidine incorporation. Subconfluent chondrocytes were synchronized in serum-free medium for 24 hours. Medium was renewed and the indicated inhibitors were added for 24 hours: indo, 50 μM indomethacin; SC-560, 10 μM; SC-236, 10 μM. Data are given as mean ± standard error of the mean, n = 6; *p value < 0.05.

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