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Table 2 Release of PGE2 into the supernatant of cultured rat chondrocytes

From: Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ – prostaglandin E2dependent proliferation of growth plate chondrocytes

Incubation time

PGE2 (μg/ml)

Proliferation status

0

120 ± 20

 

2 days

530 ± 270a

Rapidly proliferating

6 days

150 ± 30

Slowly proliferating

  1. Chondrocytes were seeded in culture plates and fresh medium was added. At different time points supernatant was collected and analyzed for prostaglandin E2 (PGE2) content (n = 6; ap < 0.01 versus day 0).
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Arthritis Research & Therapy

ISSN: 1478-6362

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