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Table 1 Classification of HLA-DRB1 alleles

From: Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

Allele classification

Amino acid sequence at positions 70–74

HLA-DRB1 alleles

S1

D-E-RAA

*0103, *0402, *1102, *1103, *1301, *1302, *1304, *1323

 

Q-A-RAA

*15

S2

Q-K-RAA

*0401

 

D-K-RAA

*1303

S3D

D-R-RAA

*1101, *1104, *12, *1305, *1306, *1325, *1422, *16

S3P

Q-R-RAA

*0101, *0102, *0404, *0405, *0408

 

R-R-RAA

*1001

X

Q-K-RGR

*03

 

Q-R-RAE

*0403, *0407, *0411

 

D-R-RGQ

*07

 

D-R-RAL

*08

 

R-R-RAE

*0901, *1401, *1404

  1. This classification of alleles, observed in our samples, is according to the amino acid sequence at positions 70–74, as described by Tezenas du Montcel and coworkers [6].