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Table 3 Results of the odds ratio calculation on the global sample (samples A and B combined)

From: Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

Genotypes Genotype distribution (n [%])   Odds ratio 95% Confidence interval
  RA index (n = 200) Pseudo-controlsa (n = 600)   
S2/S2 14 (7) 17 (2.8) 20.5 7.1–58.8
S2/S3P 36 (18) 34 (5.7) 22.2 9.9–49.7
S2/L 44 (22) 120 (20) 5.9 2.9–12.2
S3P/S3P 15 (7.5) 31 (5.2) 8.2 3.2–21.2
S3P/L 58 (29) 164 (27.3) 4.4 2.3–8.4
L/L 33 (16.5) 234 (39) 1 -
  1. Alleles S2, S3P and L are defined according to amino acid sequence at positions 70–74, as described in Table 1. The L alleles are the low-risk alleles S1, S3D and X. The reference genotype is L/L. aPseudo-controls are the three other genotypes that could be formed by the parental genotypes.