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Table 1 Clinical characteristics and lipid profile of patients with early rheumatoid arthritis and controls

From: Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment – a prospective, controlled study

 

Controls (N = 63)

Patients

  

Baseline (N = 58)

Post treatment (N = 56)

Sex (male/female)

20/43

14/44

13/43

Age (years)

58.4 ± 17.7

53.6 ± 15.3

54.7 ± 14.8

Body mass index (kg/m2)

25.8 ± 17.7

25.5 ± 3.3

25.8 ± 3.1

IgM rheumatoid factor (+/-)

0/0

45/13

44/13

C-reactive protein (mg/dl)

2.1 ± 1.3

28.15 ± 20.75

4.60 ± 4.20a

ESR (mm/h)

5.2 ± 3.1

48.0 ± 19.7

14.6 ± 8.7a

DAS-28

-

5.8 ± 0.9

2.7 ± 1.0a

TC (mg/dl)

190.4 ± 33.9

216.5 ± 50.3b

228.1 ± 42.1c

LDL-C (mg/dl)

126.5 ± 31.3

141.6 ± 42.3b

140.4 ± 32.4

HDL-C (mg/dl)

51.1 ± 7.4

47.5 ± 11.82

60.7 ± 13.4a

NonHDL-C (mg/dl)

139.3 ± 30.2

172.0 ± 46.3b

167.4 ± 37.4

Triglycerides (mg/dl)

97.1 ± 28.3

133.0 ± 58.2b

131.5 ± 56.1

TC/HDL-C

3.7 ± 0.9

4.9 ± 1.3b

3.8 ± 0.8a

LDL-C/HDL-C

2.5 ± 0.8

3.0 ± 1.0b

2.4 ± 0.6a

Apolipoprotein B (mg/dl)

93 ± 19

103 ± 28b

105 ± 30

Apolipoprotein A-I (mg/dl)

144 ± 23

127 ± 27d

152 ± 22a

  1. Values represent the mean ± standard deviation. ap < 0.001 and cp < 0.05 compared to the baseline values; bp < 0.001 and dp < 0.01 compared to the control group. DAS-28, disease activity for 28 joint indices score; ESR, erythrocyte sedimentation rate; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol.
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Arthritis Research & Therapy

ISSN: 1478-6362

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