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Table 1 Clinical characteristics and lipid profile of patients with early rheumatoid arthritis and controls

From: Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment – a prospective, controlled study

  Controls (N = 63) Patients
   Baseline (N = 58) Post treatment (N = 56)
Sex (male/female) 20/43 14/44 13/43
Age (years) 58.4 ± 17.7 53.6 ± 15.3 54.7 ± 14.8
Body mass index (kg/m2) 25.8 ± 17.7 25.5 ± 3.3 25.8 ± 3.1
IgM rheumatoid factor (+/-) 0/0 45/13 44/13
C-reactive protein (mg/dl) 2.1 ± 1.3 28.15 ± 20.75 4.60 ± 4.20a
ESR (mm/h) 5.2 ± 3.1 48.0 ± 19.7 14.6 ± 8.7a
DAS-28 - 5.8 ± 0.9 2.7 ± 1.0a
TC (mg/dl) 190.4 ± 33.9 216.5 ± 50.3b 228.1 ± 42.1c
LDL-C (mg/dl) 126.5 ± 31.3 141.6 ± 42.3b 140.4 ± 32.4
HDL-C (mg/dl) 51.1 ± 7.4 47.5 ± 11.82 60.7 ± 13.4a
NonHDL-C (mg/dl) 139.3 ± 30.2 172.0 ± 46.3b 167.4 ± 37.4
Triglycerides (mg/dl) 97.1 ± 28.3 133.0 ± 58.2b 131.5 ± 56.1
TC/HDL-C 3.7 ± 0.9 4.9 ± 1.3b 3.8 ± 0.8a
LDL-C/HDL-C 2.5 ± 0.8 3.0 ± 1.0b 2.4 ± 0.6a
Apolipoprotein B (mg/dl) 93 ± 19 103 ± 28b 105 ± 30
Apolipoprotein A-I (mg/dl) 144 ± 23 127 ± 27d 152 ± 22a
  1. Values represent the mean ± standard deviation. ap < 0.001 and cp < 0.05 compared to the baseline values; bp < 0.001 and dp < 0.01 compared to the control group. DAS-28, disease activity for 28 joint indices score; ESR, erythrocyte sedimentation rate; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol.