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Table 2 Rate of change for subjects completing follow-up, over the total, first and second time periods

From: Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years

Parameter

4.5 yearsa

First period: 0–2 yearsa

Second period: 2–5 yearsa

Difference (95% CI)

Annual rate of cartilage loss, mm3/year

   Total

135 (135)

143 (247)

125 (144)

18 (- 46 to 81)

   Medial

63 (78)

69 (149)

56 (85)

12 (- 28 to 52)

   Lateral

72 (73)

75 (140)

69 (77)

6 (- 31 to 42)

Annual percentage cartilage loss

   Total

3.94 (3.68)

4.04 (7.25)

4.11 (4.39)

- 0.07 (- 1.91 to 1.76)

   Medial

3.74 (4.72)

3.87 (9.49)

3.77 (5.88)

0.10 (- 2.44 to 2.64)

   Lateral

4.42 (4.65)

4.60 (9.10)

4.80 (5.60)

- 0.20 (- 2.40 to 1.99)

  1. CI, confidence interval. aMean (SD).