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Table 2 Rate of change for subjects completing follow-up, over the total, first and second time periods

From: Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years

Parameter 4.5 yearsa First period: 0–2 yearsa Second period: 2–5 yearsa Difference (95% CI)
Annual rate of cartilage loss, mm3/year
   Total 135 (135) 143 (247) 125 (144) 18 (- 46 to 81)
   Medial 63 (78) 69 (149) 56 (85) 12 (- 28 to 52)
   Lateral 72 (73) 75 (140) 69 (77) 6 (- 31 to 42)
Annual percentage cartilage loss
   Total 3.94 (3.68) 4.04 (7.25) 4.11 (4.39) - 0.07 (- 1.91 to 1.76)
   Medial 3.74 (4.72) 3.87 (9.49) 3.77 (5.88) 0.10 (- 2.44 to 2.64)
   Lateral 4.42 (4.65) 4.60 (9.10) 4.80 (5.60) - 0.20 (- 2.40 to 1.99)
  1. CI, confidence interval. aMean (SD).