Table 1 Demographic and genetic data of Austrian rheumatoid arthritis patients and matched control subjects
From: The MHC2TA-168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients
Patients (n = 362) | Controls (n = 351) | P value | |
|---|---|---|---|
Male gender (n (%)) | 70 (19.3) | 70 (19.9) | n.s. |
Age (years ± SD) | 59 ± 13 | 59 ± 11 | n.s. |
Disease duration (years ± SD) | 9 ± 5 | - | - |
Erosive disease (%) | 76 | - | - |
DMARDs (n ± SD) | 6 ± 2 | - | - |
MHC2TA -168 AA genotype (n (%)) | 184 (50.8) | 172 (49.0) | - |
MHC2TA -168 AG genotype (n (%)) | 155 (42.8) | 142 (40.5) | 0.90 (AG genotype versus AA genotype) |
MHC2TA -168 GG genotype (n (%)) | 23 (6.4) | 37 (10.5) | 0.044 (GG genotype versus AA + AG genotypes) |
MHC2TA -168G frequency | 0.278 | 0.308 | 0.21 |