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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Inhibitory effect of ribbon-type NF-κB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo

Figure 2

The stability and binding activity of RNODN and PNODN. (a) Stability of phosphorothionate double-stranded NF-κB decoy oligodeoxynucleotide (PNODN) and ribbon-type NF-κB decoy oligodeoxynucleotide (RNODN) in the presence of exonuclease III. (b) Effects of various decoys on binding activity towards NF-κB. The binding activity of decoy oligodeoxynucleotides (ODNs) reflected their ability to decrease absorbance. NE, nuclear extract without treatment of decoy ODN. (n = 5 per group; *p < 0.05, **p < 0.01, #p < 0.05, ##p < 0.01, ###p < 0.001 compared with nuclear extract without treatment of decoy ODN.)

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