Table 1 Clinical characteristics of patients
Characteristic | SSc patients | Â | Healthy controls |
|---|---|---|---|
| Â | With PAH | Without PAH | Â |
Number at entry (n (male:female) | 20 (1:19) | 58 (5:53) | 95 (8:87) |
Age (years; mean (range) | 48.6 (17–80) | 47.7 (19–77) | 40.9 (22–78) |
Diffuse SSc:limited SSc (n) | 6:14 | 33:25 | Â |
Disease duration (months; mean (range) | 42.0 (6–130) | 41.9 (5–120) |  |
Pulmonary fibrosis (n (%) | 6 (30) | 31 (53) | Â |
Frequency of ANA (n (%) | |||
   Anti-U1-snRNP antibody | 11 (55) | 17 (29) | 0 |
   Anti-topoisomerase I antibody | 1 (5) | 13 (22) | 0 |
   Anti-centromere antibody | 5 (25) | 12 (21) | 0 |