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Table 3 Allele frequencies for the CCTTT-repeat polymorphism

From: NOS2polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activity

Allele

SSc patients

Healthy controls

 

With PAH

Without PAH

 

6

2

0

0

7

2

0

0

8

8

0

4

9

6

4

8

10

10

11

19

11

5

16

25

12

6

29

42

13

0

22

32

14

1

14

29

15

0

7

13

16

0

4

13

17

0

4

4

18

0

2

1

19

0

2

0

20

0

0

0

21

0

1

0

  1. P < 0.0001 for patients with both SSc and PAH compared with healthy control subjects by the Mann-Whitney U test. P < 0.0001 for patients with both SSc and PAH compared with patients with SSc but not PAH by the Mann-Whitney U test. PAH, pulmonary arterial hypertension; SSc, systemic sclerosis.