Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

Table 2 Anti-type II collagen antibody staining on neonatal cartilage

Strain	n	Area fraction^a
C9T-BQ	8	17.2 ± 9.8^b
B10.Q	8	6.5 ± 1.8^b

Sections were obtained and stained as described in materials and methods from pure-line homozygous C9T-BQ and wild-type controls (B10.Q). Where errors are shown, results are means ± SD. ^aArea fraction is calculated as the stained area as a percentage of the total area, from one joint per individual. ^bC9T-BQ animals had a significantly more densely stained area (p = 0.009) than their wild-type counterpart.

ISSN: 1478-6362