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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation

Figure 3

Expression of 11β-HSD1 in synovial tissue. Co-localization of 11β-HSD1 with markers of endothelial cells (vWF), fibroblasts (ASO2/CD90), T-cells (CD3), dendritic cells (CD11c) and lining macrophages (lining mac; CD68). Fluorescence immunohistochemistry was carried out using green, red and blue fluorescent tagged antiserum as shown in each panel. In each case the scale bar is 20 μm. A indicates co-expression of 11β-HSD1 and ASO2 (CD90) in fibroblasts; B highlights co-expression of 11β-HSD1 and vWF in endothelial cells. 11β-HSD, 11β-hydroxysteroid dehydrogenase type 1; vWF, von Willebrand factor.

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Arthritis Research & Therapy

ISSN: 1478-6362

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