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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation

Figure 6

Expression of 11β-HSD1 in fibroblasts correlates with C/EBPα and C/EBPβ. (a) Correlation between ΔCt values for C/EBPα and C/EBPβ with ΔCt values for 11β-HSD1 in all fibroblast populations. (b) Fold change in C/EBP expression in bone marrow and synovial fibroblasts relative to dermal fibroblasts (mean ± standard deviation). *P < 0.01 versus dermal and bone marrow fibroblasts (statistical analysis carried out on ΔCt values). C/EBP = CCAAT/enhancer binding protein; Ct = the cycle number at which logarithmic PCR plots cross a calculated threshold line; 11β-HSD = 11β-hydroxysteroid dehydrogenase.

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