Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases

Table 1 Cases with anti-RPA autoantibodies

Case	Age	Sex	Race	Diagnosis	SLE criteria	ELISA (unit)	Western blot
							RPA70	RPA32	RPA14
1	27	F	Black	SLE	7	189.0	++	++	+
2	45	F	Latin	SLE	5	11.5	++	++	+
3	35	F	Mixed	SLE	4	19.6	+	++	+
4	23	M	Black	SLE	6	27.0	-	-	-
5	41	F	White	Possible SLE	3	149.1	+	++	-
6	61	F	White	SjS, PBC	1	125	++	++	+
7	56	F	Black	ILD	1	> 625	+	++	+
8	48	F	White	Thyroiditis, HCV, pernicious anemia	1	81.8	+	++	+
9	51	F	Black	Unknown	1	34.4	-	-	+

SLE, systemic lupus erythematosus; SjS, Sjögren syndrome; PBC, primary biliary cirrhosis; ILD, interstitial lung disease; HCV, hepatitis C virus infection; ELISA, enzyme-linked immunosorbent assay; RPA, replication protein A.

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