From: Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
New biologic therapy
Reason for withdrawal
Total
Lack of efficacy
Patient request
Safety issues
None
24
3
44
71
Adalinumab
10
23
36
Etanercept
6
4
8
18
Rituximab
0
1
9
Abatacept
52
30
60
142