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Figure 5 | Arthritis Research & Therapy

Figure 5

From: The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

Figure 5

Proliferative responses of CD4+ T cells upon incubation with supernatants from T cell clones (TCCs). CD4+ T cells of two healthy controls (HC-1, HC-2) and two systemic lupus erythematosus (SLE) patients (SLE-1, SLE-2) were stimulated with platebound anti-CD3/anti-CD28 mAbs. Cells were incubated for 24 hours with the supernatants of a CD4+CD28+ and a CD8+CD28- TCC derived from an SLE patient, and proliferation was measured after an additional 16 hours. The increase in proliferation was statistically significant for all supernatants examined (indicated by a star).

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Arthritis Research & Therapy

ISSN: 1478-6362

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