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Table 2 Proliferative responses to hnRNP-A2 and the control antigen tetanus toxoid in SLE patients and healthy controls

From: The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

 

Proliferative response to

 
 

hnRNP-A2

Tetanus toxoid

P value

SLE patients (n = 21)

7.5 ± 1.2

6.2 ± 1.1

P < 0.05

Healthy controls (n = 16)

2.5 ± 0.6

5.0 ± 1.4

P < 0.002

P value

P < 0.000002

NS

 
  1. Data are given as mean stimulation index ± SEM. Student's paired t-test was used to calculate statistical significances. hnRNP, heterogeneous nuclear ribonucleoprotein; NS, not significant; SLE, systemic lupus erythematosus.