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Table 2 Comparison of sensitivity and specificity of the anti-modified citrullinated vimentin and the anti-cyclic citrullinated peptide test (n = 467)

From: Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis

 

Cutoff (U/ml)

Sensitivity (% [95% CI])

Specificity (% [95% CI])

Anti-MCV

20.0a

69.5 (61.9–76.5)

90.8 (86.9–93.8)

 

19.0b

70.1 (62.5–77.0)

89.8 (85.8–92.9)

 

81.5c

53.7 (45.7–61.5)

98.7 (96.7–99.6)

Anti-CCP2

10.0a

70.1 (62.5–77.0)

98.7 (96.7–99.6)

  1. aRecommended by the manufacturer. Cutoff with identical sensitivityb and specificityc compared with the anti-CCP2 test, respectively.
  2. anti-CCP2, second-generation anti-cyclic citrullinated peptide; anti-MCV, anti-modified citrullinated vimentin; CI, confidence interval.
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Arthritis Research & Therapy

ISSN: 1478-6362

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