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Table 3 Sensitivities of the different ACPA assays in population 2 after dichotomization at specificity level ≥ 98%

From: Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays

 

Sensitivity

Cut-off (at 98% specificity)

Ref.

AhFibA

70%

0.12 OD

[18]

Anti-CCP1

51%

92 U/ml

[11]

Anti-CCP2

65%

42 U/ml

[14]

Anti-PepA

57%

1

[13,14]

Anti-PepB

55%

1

[13,14]

  1. ACPA, anti-citrullinated protein/peptide antibody; AhFibA, anti-human fibrinogen (auto)antibodies; CCP, cyclic citrullinated peptide; OD, optical density.