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Figure 2 | Arthritis Research & Therapy

Figure 2

From: A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis

Figure 2

Correlation between the level of proteolytic activity found and the number of infiltrating leukocytes. Positive correlation between the net proteolytic activity (NPA) and the number of (a) infiltrating leukocytes (rs = 0.710, P < 0.001) or (b) polymorphonuclear cells (PMN) (rs = 0.696, P < 0.001) in synovial fluids of patients with inflammatory arthritis. (c) No such correlation between the NPA and the number of infiltrating leukocytes was observed in osteoarthritis (OA) patients. Each point represents one sample. The correlation was calculated using Spearman's rank correlation coefficient for each test. FASC, fluorescent-activated substrate conversion.

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