Study population
|
1.
|
Patients with radiographically confirmed osteoarthritis or selected according to American College of Rheumatology guidelines
|
2.
|
Age, gender, and body mass index reported and not statistically different between groups
|
3.
|
Efficacy assessed on a single anatomical joint (for example, knee)
|
Trial design
|
4.
|
Randomisation
|
5.
|
Placebo-controlled study
|
6.
|
Double-blind study
|
7.
|
Duration of at least 3 months
|
8.
|
Selection of a single primary endpoint before beginning of trial
|
9.
|
Sample size based on power calculation
|
Analysis and data presentation
|
10.
|
Data analysed according to the intention-to-treat principle
|
11.
|
Reported dropout rate not more than 25%
|
12.
|
Report of adverse effects
|