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Table 1 Radiographic damage in patients stratified for RF and anti-CCP status

From: Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis

Antibody status n Larsen's score (mean ± SEM) P
RF positive 552 49.1 ± 1.7 <0.0001a
RF negative 268 33.0 ± 1.9  
Anti-CCP positive 672 46.9 ± 1.5 <0.0001a
Anti-CCP negative 159 31.3 ± 2.4  
RF positive/CCP positive 493 49.6 ± 1.8 <0.0001b
RF positive/CCP negative 39 37.6 ± 5.2  
RF negative/CCP positive 143 37.2 ± 2.7  
RF negative/CCP negative 109 28.0 ± 2.8  
  1. Shown is an analysis of radiographic damage, as assessed by modified Larsen's score, in patients stratified for RF and anti-CCP status. at-test. bComparison of four groups by analysis of variance. anti-CCP, anti-cyclic citrullinated peptide antibody; RF, rheumatoid factor; SEM, standard error of the mean.