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Table 3 Association between SE alleles and anti-CCP status

From: Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis

RF status Number of SE alleles Proportion anti-CCP positive OR (95% CI) P
All 2 214/241 4.94 (2.94–8.22) <0.001
  1 307/373 2.90 (1.89–4.43)  
  0 98/159 1  
RF positive 2 162/170 4.15 (1.79–9.58) <0.01
  1 236/253 2.85 (1.41–5.77)  
  0 78/94 1  
RF negative 2 52/71 6.16 (3.00–12.6) <0.001
  1 71/120 3.26 (1.74–6.11)  
  0 20/65 1  
  1. Absolute numbers of anti-CCP-positive patients in each subgroup are given. OR with 95% CI are shown for anti-CCP positivity associated with carriage of two or one SE allele versus no SE alleles for RF positive, RF negative and combined subgroups. P values are for χ2 tests with two degrees of freedom comparing the proportion of anti-CCP positive patients in subgroups carrying two, one, or no SE alleles. anti-CCP, anti-cyclic citrullinated peptide antibody; CI, confidence interval; NS, not significant; OR, odds ratio; RF, rheumatoid factor; SEM, standard error of the mean.