Figure 6

Histological joint sections from arthritic mice with CII-pulsed treated dendritic cells. H & E-stained sagittal sections of proximal interphalangeal joints from collagen-induced arthritis mice. (a) Control mouse shows severe edema, congestion, and monocyte infiltration; the bone surface became uneven. (b) The majority of joints from mice injected with LF 15-0195-treated dendritic cells have normal morphology with a smooth articulation cartilage surface, and an absence of inflammatory cell infiltrate and edema. Original magnification × 100.