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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis

Figure 3

Negative correlation of bone marrow edema in histopathological assessment and magnetic resonance imaging. (a) Magnetic resonance imaging of zygapophyseal joints (cyan arrows) without detectable bone marrow edema (asterisk, vertebral body; open square, epidural space; plus signs, superior and inferior articular processes of the zygapophyseal joint; hash sign, processus spinosus). (b) Hematoxylin and eosin staining of the zygapophyseal joint, revealing numerous mononuclear cells in the bone marrow (yellow arrow) and a relatively small amount of edema (20%) in the bone marrow (red arrow). (c) Immunohistochemical analysis of CD3+ T cells (red arrow), showing dense infiltrates of CD3+ T cells (yellow arrow).

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