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Table 5 Zonal distribution of proteoglycan

From: Long-term cyclical in vivoloading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study

  Normalized PG in superficial zonea Normalized PG in mid zoneb Normalized PG in deep zonec
Rabbit no. Control Loaded Difference Control Loaded Difference Control Loaded Difference
1 0.14 0.20 0.06 0.06 0.29 0.23 0.03 0.11 0.08
2 0.05 0.01 -0.04 0.09 0.06 -0.02 0.06 0.09 0.03
3 0.27 0.33 0.06 0.22 0.31 0.09 0.19 0.28 0.09
4 0.27 0.18 -0.08 0.13 0.19 0.05 0.07 0.14 0.07
5 0.18 0.17 -0.01 0.17 0.16 -0.01 0.14 0.18 0.04
6 0.06 0.17 0.11 0.15 0.15 0.00 0.18 0.22 0.04
Mean 0.16 0.18 0.02 0.14 0.20 0.06 0.11 0.17 0.06
SD 0.09 0.10 0.07 0.06 0.09 0.10 0.07 0.07 0.03
Significanced    >0.05    >0.05    0.003
  1. aSuperficial zone of cartilage is from 0 to 8 μm; bmid zone is from 8 to 53 μm; cdeep zone is from 53 to 100 μm; the zone thicknesses were determined by polarized light microscopy; dsignificance was calculated using the two-tailed, paired Student t test (α = 0.05). PG, proteoglycan; SD, standard deviation.