Figure 2From: Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic miceBinding of analog peptides to DRB1*0401. IC50 (50% inhibitory concentration) values are the average of two determinations per peptide. Peptides binding to DRB1*0401 with an IC50 of about 1,000 are represented by striped bars (264A, 266D). Peptides binding to DRB1*0401 with an IC50 of 100 or less (comparable to wild-type peptide binding) are represented by white bars.Back to article page