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Table 1 Characteristics of rheumatoid arthritis patients with and without cardiovascular disease

From: Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study

  RA without CVD (n = 541) RA with CVD (n = 72) p value
Demographic variables    
   Mean age, years (SD) 62 (11) 67 (10) <0.001a
   Percentage females 72 58 0.02a
RA related variables    
   Median disease duration, years (IQ range) 7.7 (5–11) 10.6 (8–13) <0.001a
   Percentage IgM-RF positive 70 82 0.05a
   Percentage erosive patients 80 92 0.02a
   Median number of used DMARDs (IQ range) 2 (2–3) 3 (1–3) 0.01a
   Percentage DMARD naive patients 3 10 0.002a
   Percentage never SSZ, HCQ or MTX 5 17 <0.001a
   Percentage SSZ ever 78 65 0.02a
   Percentage HCQ ever 40 38 0.67
   Percentage MTX ever 72 44 <0.001a
   Percentage prednisone ever 31 25 0.32
CVD related variables    
   Percentage smoking ever 64 65 0.83
   Percentage hypertension 19 49 <0.001a
   Percentage diabetes 5 10 0.14
   Percentage hypercholesterolemia 2 21 <0.001a
  1. Comparison made using Students' t-tests or Mann-Whitney U tests for the continues variables and Pearson's Chi-square tests for dichotomic variables. aSignificant. CVD, cardiovascular disease; DMARD, disease modifying anti-rheumatic drug; HCQ, hydroxychloroquine; IQ range, inter-quartile-range; MTX, methotrexate; RA, rheumatoid arthritis; RF, rheumatoid factor; SD, standard deviation; SSZ, sulfasalazine.