|
Groups
|
Model 1 OR (95 percent CI)
|
Model 2 OR (95 percent CI)
|
Model 3 OR (95 percent CI)
|
|---|
|
Never MTX, SSZ or HCQ (reference)
|
1.0
|
1.0
|
1.0
|
|
Only MTX ever
|
0.16 (0.04–0.66)a
|
0.47 (0.07–3.23)
|
0.11 (0.02–0.56)a
|
|
Only SSZ ever
|
0.42 (0.16–1.10)
|
0.31 (0.07–1.33)
|
0.37 (0.14–0.99)a
|
|
Only HCQ ever
|
0.55 (0.18–1.67)
|
0.45 (0.10–2.04)
|
0.47 (0.15–1.46)
|
|
MTX and SSZ ever
|
0.20 (0.08–0.51)a
|
0.24 (0.07–0.85)a
|
0.16 (0.06–0.42)a
|
|
MTX and HCQ ever
|
0.22 (0.04–1.19)
|
0.54 (0.08–3.66)
|
0.19 (0.04–1.02)
|
|
SSZ and HCQ ever
|
0.44 (0.14–1.41)
|
0.34 (0.05–2.16)
|
0.37 (0.11–1.24)
|
|
MTX, SSZ and HCQ ever
|
0.20 (0.08–0.54)a
|
0.27 (0.07–0.99)a
|
0.16 (0.06–0.43)a
|
- Model 1: correcting for age, gender, smoking and rheumatoid arthritis duration. Model 2: identical to 'Model 1' plus correction for hypertension, diabetes and hypercholesterolemia. Model 3: identical to 'Model 1' plus correction for a positive rheumatoid factor test and erosions. aSignificant. CI, confidence interval; HCQ, hydroxychloroquine; MTX, methotrexate; OR, odds ratio; SSZ, sulfasalazine.
