Figure 1From: Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?Clearance of apoptotic cells from irradiated skin in patients with systemic lupus erythematosus (SLE) compared with controls. Representative images of skin sections stained for cleaved caspase-3 (a) 1 day, (b) 3 days, and (c) 10 days after irradiation with two minimal erythemal doses of ultraviolet B light (UVB). Arrowheads indicate cleaved caspase-3-positive cells. Magnifications, ×200. (d) Graph showing numbers of sunburn cells (SBCs) per square millimeter in patients (n = 15) and controls (n = 13). (e) Number of cleaved caspase-3-positive keratinocytes per square millimeter. ●, patients (P); ○, controls (C). Median is indicated by a horizontal line. (f) A representative hematoxylin eosin (H&E)-stained section after irradiation with UVB, showing SBCs (white arrowheads) and nuclear dust (black arrows indicate one intact pyknotic nucleus, white arrow indicates pyknotic fragmented nucleus).Back to article page